Diagnosis and management of Cornelia de Lange Syndrome
first international consensus statement
(Adapted for easy access and wider distribution).
- What is Cornelia de Lange Syndrome?
- What causes Cornelia de Lange Syndrome?
- How is Cornelia de Lange Syndrome Diagnosed?
- What medical care may a child with CdLS need?
- What health difficulties might a child with CdLS face?
- What are the Cognitive and Behavioural Characteristics of Cornelia de Lange Syndrome?
- Do Cognitive and Behavioural Characteristics Change with Age in CdLS?
- Care Planning in CdLS
- Full List of Recommendations
- References
- Supplementary Box 1. Cornelia de Lange syndrome emergency card
- Table 3. Studies reporting level of intellectual disability in individuals with Cornelia de Lange syndrome.
- Table 4. Studies reporting level of developmental delay in individuals with Cornelia de Lange syndrome
Adapted from: Kline, A. D., Moss, J. F., Selicorni, A., Bisgaard, A., Deardorff, M. A., Gillett, P. M., Ishman, S. L., Kerr, L. M., Levin, A. V., Mulder, P. A., Ramos, F. J., Wierzba, J., Ajmone, P.F., Axtell, D., Blagowidow, N., Cereda, A., Costantino, A., Cormier-Daire, V., FitzPatrick, D., Grados, M., Groves, L., Guthrie, W., Huisman, S., Kaiser, F. J., Koekkoek, G., Levis, M., Mariani, M., McCleery, J. P., Menke, L. A., Metrena, A., O’Connor, J., Oliver, C., Pie, J., Piening, S., Potter, C. J., Quaglio, A. L., Redeker, E., Richman, D., Rigamonti, C., Shi, A., Tümer, Z., Van Balkom, I. D. C. and Hennekam, R. C. (2018). Diagnosis and management in Cornelia de Lange Syndrome: First international consensus statement. Nature Reviews Genetics, 19, 649-666.
The text of these pages and figures 1, 2, 3, 4 and 5, tables 1 and 2, and box 1 are adapted from the original article.
Adaptation, the English baseline version, written by: Lauren Shelley, Rachel Royston, Chris Oliver, Tonie Kline, David Fitzpatrick, Bjorn Harris, Steve Knight, Alan Peaford, Jules Harris, David Axtell, Charlie Blockley, Sara Peaford and Natalie Blockley.
Work on the adaptation was funded by a grant from Cerebra to the University of Birmingham
Note: References to published papers will be indicated by (number), e.g. (1) or (2). The full reference for the paper can be found next to the corresponding number in the reference section at the end of the document.
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org.xwiki.rendering.macro.MacroExecutionException: Failed to evaluate Velocity Macro for content [{{html}}
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#set($topicsArray = [])
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##This will loop only once since we should only find ONE document
#set($thisTopicDoc = $xwiki.getDocument($thisTopicDocRef))
## We need to search for a diseaseTag in the topicTree
## A better algorithm for below is a recursive one, but I always struggle with that one in Velocity
## ++++++++++++++++++++++++++++++
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## =============
## Found the Topic Text, the disease with the topic, The Parent key
## ++++++++++++++++++++++++++++++
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## We have a user problem when the topic referred to has only ONE publication
## It will be $doc for the entity (informationb,Experience or question) currently viewed
## so we should count the publications that will be shown when the indexpage wil be shown, only > 1 : FOR THE CURRENT ENTITY!
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#set($tempArray = [])
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#set($storyPageRefArray = $collectionstool.union($storyPageRefArray, $tempArray))
#end
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#set($discard = $topicObject.put('answerArray', $answerPageRefArray))
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## We need more as 1 page
#if($entityType == 'information' && $topicObject.informationArray.size() > 1)
#set($discard = $linkObject.put('iconHTML', "<span class='wai-tile-icon waihonapedia-information' style='width: 1.25em; height: 1.25em;'> </span>"))
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#elseif($entityType == 'information' && $topicObject.informationArray.size() == 1)
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#set($discard = $linkObject.put('label', $parentTitle) )
#end
#set($thisURL = $xwiki.getDocument($publicationDocRef).getURL('view',"sheet=WaihonaCode.publicInfo.infoDisplayer&topic=${topicObject.parentKey}") )
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##set($docRefList = $services.query.xwql($publicationsCountQueryDef).bindValue('thisTopicKey', $topicObject.parentKey).addFilter('unique'))
##$docRefList.size() $publicationsCountQueryDef
#set($discard = $linkObject.put('count', $services.query.xwql($publicationsCountQueryDef).bindValue('thisTopicKey', $topicObject.parentKey).addFilter('unique').count() ))
#elseif($entityType == 'story' && $topicObject.storyArray.size() > 1)
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#elseif($entityType == 'story' && $topicObject.storyArray.size() == 1)
## we might have the situation that the current page is the only story with this topic
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#foreach($parentTopicDocRef in $parentTopicDocRefList) ## we expect only one
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#set($discard = $linkObject.put('label', $parentTitle) )
#end
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#set($story1DocRefList = $services.query.xwql($storyCount1QueryDef).bindValue('thisTopicKey', $topicObject.parentKey).addFilter('unique'))
#set($story2DocRefList = $services.query.xwql($storyCount2QueryDef).bindValue('thisTopicKey', $topicObject.parentKey).addFilter('unique'))
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#elseif($entityType == 'answer' && $topicObject.answerArray.size() > 1)
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#set($discard = $linkObject.put('label', $thisTopicDoc.getTranslatedDocument().getPlainTitle()) )
#set($thisURL = $xwiki.getDocument('ATEPublic.topicATEDisplayer').getURL('view', "searchOrigin=topic&topic=${thisKey}&atepage=overview") )
#set($discard = $linkObject.put('url', $thisURL) )
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#elseif($entityType == 'answer' && $topicObject.answerArray.size() == 1)
#set($discard = $linkObject.put('iconHTML', "<span class='wai-tile-icon waihonapedia-answers' style='width: 1.25em; height: 1.25em;'> </span>"))
#set($parentTopicDocRefList = $services.query.xwql($topicQueryDef).bindValue('thisKey', $topicObject.parentKey).addFilter('unique').execute() )
#foreach($parentTopicDocRef in $parentTopicDocRefList) ## we expect only one
#set($parentTitle = $xwiki.getDocument($parentTopicDocRef).getTranslatedDocument().getPlainTitle())
#set($discard = $linkObject.put('label', $parentTitle) )
#end
#set($thisURL = $xwiki.getDocument('ATEPublic.topicATEDisplayer').getURL('view', "searchOrigin=topic&topic=${topicObject.parentKey}&atepage=overview") )
#set($discard = $linkObject.put('url', $thisURL) )
#set($discard = $linkObject.put('count', $services.query.xwql($ateCountQueryDef).bindValue('thisTopicKey', $topicObject.parentKey).addFilter('unique').count() ))
#end
#else ## 1 or more pages needed
#if($entityType == 'information' && $topicObject.informationArray.size() > 0)
#set($discard = $linkObject.put('iconHTML', "<span class='wai-tile-icon waihonapedia-information' style='width: 1.25em; height: 1.25em;'> </span>"))
#set($discard = $linkObject.put('label', $thisTopicDoc.getTranslatedDocument().getPlainTitle()) )
#set($thisURL = $xwiki.getDocument($publicationDocRef).getURL('view',"sheet=WaihonaCode.publicInfo.infoDisplayer&topic=${thisKey}"))
#set($discard = $linkObject.put('url', $thisURL ))
#set($discard = $linkObject.put('count', $topicObject.informationArray.size()))
#elseif($entityType == 'story' && $topicObject.storyArray.size() > 0)
#set($discard = $linkObject.put('iconHTML', "<span class='wai-tile-icon waihonapedia-stories' style='width: 1.25em; height: 1.25em;'> </span>"))
#set($discard = $linkObject.put('label', $thisTopicDoc.getTranslatedDocument().getPlainTitle()) )
#set($thisURL = $xwiki.getDocument($publicationDocRef).getURL('view',"sheet=WaihonaCode.publicInfo.storyDisplayer&topic=${thisKey}"))
#set($discard = $linkObject.put('url', $thisURL ))
#set($discard = $linkObject.put('count', $topicObject.storyArray.size() ))
#elseif($entityType == 'answer' && $topicObject.answerArray.size() > 1)
#set($discard = $linkObject.put('iconHTML', "<span class='wai-tile-icon waihonapedia-answers' style='width: 1.25em; height: 1.25em;'> </span>"))
#set($discard = $linkObject.put('label', $thisTopicDoc.getTranslatedDocument().getPlainTitle()) )
#set($thisURL = $xwiki.getDocument('ATEPublic.topicATEDisplayer').getURL('view', "searchOrigin=topic&topic=${thisKey}&atepage=overview") )
#set($discard = $linkObject.put('url', $thisURL) )
#set($discard = $linkObject.put('count', $topicObject.answerArray.size() ))
#end
#end
#set($discard = $topicObject.put($entityType, $linkObject) )
#end
#set($discard = $topicsArray.add($topicObject))
#end ## foreach topicTag
#*
* info: $infoPageRefArray $topicsArray $topicsArray.size()
* ate $atePageRefArray
* story $storyPageRefArray
*#
#if($topicTags.size()>0 && $topicsArray.size()>0 )
<div class='meta-topics'>
<span class='meta-topics-label'>$services.localization.render('waihonapedia.meta.topics.title')</span>
<span class="topics-with-page">
#foreach($topicObject in $topicsArray)
#foreach($entityType in ['information','story','answer'])
#set($infoObject = $topicObject.get($entityType) )
#if ($infoObject.count > 0 || $entityType == $thisPageEntity )
#if($infoObject.show != 'false')
<span class="label topic-link"><a href="${infoObject.url}" target="blank"><span class='wai-tile-icon-area'>$infoObject.iconHTML</span>${infoObject.label}#if($infoObject.count > 0)<span class='badge badge-light'>$infoObject.count</span>#end</a></span>
#end
#end
#end
#end
</span>
</div>
#end
#end
{{/html}}]
at org.xwiki.rendering.internal.macro.velocity.VelocityMacro.evaluateString(VelocityMacro.java:135)
at org.xwiki.rendering.internal.macro.velocity.VelocityMacro.evaluateString(VelocityMacro.java:51)
at org.xwiki.rendering.macro.script.AbstractScriptMacro.evaluateBlock(AbstractScriptMacro.java:279)
at org.xwiki.rendering.macro.script.AbstractScriptMacro.execute(AbstractScriptMacro.java:182)
at org.xwiki.rendering.macro.script.AbstractScriptMacro.execute(AbstractScriptMacro.java:58)
at org.xwiki.rendering.internal.transformation.macro.MacroTransformation.transform(MacroTransformation.java:309)
at org.xwiki.rendering.internal.transformation.DefaultRenderingContext.transformInContext(DefaultRenderingContext.java:183)
at org.xwiki.rendering.async.internal.block.AbstractBlockAsyncRenderer.transform(AbstractBlockAsyncRenderer.java:76)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRenderer.tranform(DefaultBlockAsyncRenderer.java:154)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRenderer.execute(DefaultBlockAsyncRenderer.java:137)
at org.xwiki.rendering.async.internal.block.AbstractBlockAsyncRenderer.render(AbstractBlockAsyncRenderer.java:157)
at org.xwiki.uiextension.internal.WikiUIExtension.render(WikiUIExtension.java:200)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor$DecoratorWrapper.render(DefaultBlockAsyncRendererExecutor.java:67)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor$DecoratorWrapper.render(DefaultBlockAsyncRendererExecutor.java:49)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.lambda$syncRender$0(DefaultAsyncRendererExecutor.java:284)
at com.xpn.xwiki.internal.security.authorization.DefaultAuthorExecutor.call(DefaultAuthorExecutor.java:98)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:284)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.execute(DefaultBlockAsyncRendererExecutor.java:125)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.execute(DefaultBlockAsyncRendererExecutor.java:113)
at org.xwiki.uiextension.internal.AbstractWikiUIExtension.execute(AbstractWikiUIExtension.java:120)
at org.xwiki.uiextension.internal.AbstractWikiUIExtension.execute(AbstractWikiUIExtension.java:108)
at jdk.internal.reflect.GeneratedMethodAccessor381.invoke(Unknown Source)
at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.base/java.lang.reflect.Method.invoke(Method.java:566)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.doInvoke(UberspectImpl.java:571)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.invoke(UberspectImpl.java:554)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:221)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.value(ASTReference.java:704)
at org.apache.velocity.runtime.parser.node.ASTExpression.value(ASTExpression.java:75)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:167)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.render(ASTReference.java:492)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.Foreach.renderBlock(Foreach.java:309)
at org.apache.velocity.runtime.directive.Foreach.render(Foreach.java:279)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:171)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.DefaultVelocityEngine.evaluate(DefaultVelocityEngine.java:280)
at com.xpn.xwiki.render.DefaultVelocityManager.evaluate(DefaultVelocityManager.java:328)
at com.xpn.xwiki.internal.template.VelocityTemplateEvaluator.evaluateContent(VelocityTemplateEvaluator.java:95)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.evaluateContent(TemplateAsyncRenderer.java:222)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.renderVelocity(TemplateAsyncRenderer.java:177)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:138)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:54)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.lambda$syncRender$0(DefaultAsyncRendererExecutor.java:284)
at com.xpn.xwiki.internal.security.authorization.DefaultAuthorExecutor.call(DefaultAuthorExecutor.java:98)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:284)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.render(DefaultBlockAsyncRendererExecutor.java:154)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:843)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:805)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:792)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:747)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:739)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:79)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:73)
at org.xwiki.template.script.TemplateScriptService.render(TemplateScriptService.java:54)
at jdk.internal.reflect.GeneratedMethodAccessor256.invoke(Unknown Source)
at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.base/java.lang.reflect.Method.invoke(Method.java:566)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.doInvoke(UberspectImpl.java:571)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.invoke(UberspectImpl.java:554)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:221)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.render(ASTReference.java:492)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.VelocimacroProxy.render(VelocimacroProxy.java:218)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:331)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:261)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.DefaultVelocityEngine.evaluate(DefaultVelocityEngine.java:280)
at com.xpn.xwiki.render.DefaultVelocityManager.evaluate(DefaultVelocityManager.java:328)
at com.xpn.xwiki.internal.template.VelocityTemplateEvaluator.evaluateContent(VelocityTemplateEvaluator.java:95)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.evaluateContent(TemplateAsyncRenderer.java:222)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.renderVelocity(TemplateAsyncRenderer.java:177)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:138)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:54)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.lambda$syncRender$0(DefaultAsyncRendererExecutor.java:284)
at com.xpn.xwiki.internal.security.authorization.DefaultAuthorExecutor.call(DefaultAuthorExecutor.java:98)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:284)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.render(DefaultBlockAsyncRendererExecutor.java:154)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:843)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:805)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:792)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:747)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderNoException(InternalTemplateManager.java:739)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:79)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.renderNoException(DefaultTemplateManager.java:73)
at org.xwiki.template.script.TemplateScriptService.render(TemplateScriptService.java:54)
at jdk.internal.reflect.GeneratedMethodAccessor256.invoke(Unknown Source)
at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.base/java.lang.reflect.Method.invoke(Method.java:566)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.doInvoke(UberspectImpl.java:571)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.invoke(UberspectImpl.java:554)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:221)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.render(ASTReference.java:492)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.VelocimacroProxy.render(VelocimacroProxy.java:218)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:331)
at org.apache.velocity.runtime.directive.RuntimeMacro.render(RuntimeMacro.java:261)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:171)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:190)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.DefaultVelocityEngine.evaluate(DefaultVelocityEngine.java:280)
at com.xpn.xwiki.render.DefaultVelocityManager.evaluate(DefaultVelocityManager.java:328)
at com.xpn.xwiki.internal.template.VelocityTemplateEvaluator.evaluateContent(VelocityTemplateEvaluator.java:95)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.evaluateContent(TemplateAsyncRenderer.java:222)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.renderVelocity(TemplateAsyncRenderer.java:177)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:138)
at com.xpn.xwiki.internal.template.TemplateAsyncRenderer.render(TemplateAsyncRenderer.java:54)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.lambda$syncRender$0(DefaultAsyncRendererExecutor.java:284)
at com.xpn.xwiki.internal.security.authorization.DefaultAuthorExecutor.call(DefaultAuthorExecutor.java:98)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.syncRender(DefaultAsyncRendererExecutor.java:284)
at org.xwiki.rendering.async.internal.DefaultAsyncRendererExecutor.render(DefaultAsyncRendererExecutor.java:267)
at org.xwiki.rendering.async.internal.block.DefaultBlockAsyncRendererExecutor.render(DefaultBlockAsyncRendererExecutor.java:154)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:843)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:805)
at com.xpn.xwiki.internal.template.InternalTemplateManager.renderFromSkin(InternalTemplateManager.java:785)
at com.xpn.xwiki.internal.template.InternalTemplateManager.render(InternalTemplateManager.java:771)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.render(DefaultTemplateManager.java:91)
at com.xpn.xwiki.internal.template.DefaultTemplateManager.render(DefaultTemplateManager.java:85)
at com.xpn.xwiki.XWiki.evaluateTemplate(XWiki.java:2563)
at com.xpn.xwiki.web.Utils.parseTemplate(Utils.java:180)
at com.xpn.xwiki.web.XWikiAction.execute(XWikiAction.java:651)
at com.xpn.xwiki.web.XWikiAction.execute(XWikiAction.java:339)
at com.xpn.xwiki.web.LegacyActionServlet.service(LegacyActionServlet.java:114)
at javax.servlet.http.HttpServlet.service(HttpServlet.java:764)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:232)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at com.xpn.xwiki.web.ActionFilter.doFilter(ActionFilter.java:122)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.xwiki.wysiwyg.filter.ConversionFilter.doFilter(ConversionFilter.java:61)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.apache.tomcat.websocket.server.WsFilter.doFilter(WsFilter.java:52)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.xwiki.container.servlet.filters.internal.SetHTTPHeaderFilter.doFilter(SetHTTPHeaderFilter.java:63)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.xwiki.resource.servlet.RoutingFilter.doFilter(RoutingFilter.java:132)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.xwiki.container.servlet.filters.internal.SavedRequestRestorerFilter.doFilter(SavedRequestRestorerFilter.java:208)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.xwiki.container.servlet.filters.internal.SetCharacterEncodingFilter.doFilter(SetCharacterEncodingFilter.java:111)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:194)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:167)
at org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:202)
at org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:97)
at org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:544)
at org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:143)
at org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:81)
at org.apache.catalina.valves.AbstractAccessLogValve.invoke(AbstractAccessLogValve.java:698)
at org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:78)
at org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:364)
at org.apache.coyote.http11.Http11Processor.service(Http11Processor.java:624)
at org.apache.coyote.AbstractProcessorLight.process(AbstractProcessorLight.java:65)
at org.apache.coyote.AbstractProtocol$ConnectionHandler.process(AbstractProtocol.java:831)
at org.apache.tomcat.util.net.NioEndpoint$SocketProcessor.doRun(NioEndpoint.java:1651)
at org.apache.tomcat.util.net.SocketProcessorBase.run(SocketProcessorBase.java:49)
at java.base/java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1128)
at java.base/java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:628)
at org.apache.tomcat.util.threads.TaskThread$WrappingRunnable.run(TaskThread.java:61)
at java.base/java.lang.Thread.run(Thread.java:829)
Caused by: org.xwiki.velocity.XWikiVelocityException: Failed to evaluate content with namespace [xwiki:WaihonaBase.uixCollections.contentFooter.waiTopicTagsUIX^XWiki.UIExtensionClass[0]]
at org.xwiki.velocity.internal.DefaultVelocityEngine.evaluate(DefaultVelocityEngine.java:289)
at com.xpn.xwiki.render.DefaultVelocityManager.evaluate(DefaultVelocityManager.java:328)
at org.xwiki.rendering.internal.macro.velocity.VelocityMacro.evaluateString(VelocityMacro.java:127)
... 183 more
Caused by: org.apache.velocity.exception.MethodInvocationException: Invocation of method 'execute' in class org.xwiki.query.internal.ScriptQuery threw exception org.xwiki.query.QueryException: Exception while executing query. Query statement = [ select doc.fullName from XWikiDocument as doc , BaseObject as topic , com.xpn.xwiki.objects.StringProperty as topic_key1 where ( topic_key1.value = :thisKey ) and doc.fullName=topic.name and topic.className='WaihonaCode.healthTopicsClass' and topic_key1.id.id=topic.id and topic_key1.id.name='key' ] at xwiki:WaihonaBase.uixCollections.contentFooter.waiTopicTagsUIX^XWiki.UIExtensionClass[0][line 210, column 133]
at org.apache.velocity.runtime.parser.node.ASTMethod.handleInvocationException(ASTMethod.java:308)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:235)
at org.apache.velocity.runtime.parser.node.ASTReference.execute(ASTReference.java:368)
at org.apache.velocity.runtime.parser.node.ASTReference.value(ASTReference.java:704)
at org.apache.velocity.runtime.parser.node.ASTExpression.value(ASTExpression.java:75)
at org.apache.velocity.runtime.parser.node.ASTSetDirective.render(ASTSetDirective.java:242)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.ASTElseIfStatement.render(ASTElseIfStatement.java:108)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:190)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:171)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.Foreach.renderBlock(Foreach.java:309)
at org.apache.velocity.runtime.directive.Foreach.render(Foreach.java:279)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.directive.Foreach.renderBlock(Foreach.java:309)
at org.apache.velocity.runtime.directive.Foreach.render(Foreach.java:279)
at org.apache.velocity.runtime.parser.node.ASTDirective.render(ASTDirective.java:304)
at org.apache.velocity.runtime.parser.node.ASTBlock.render(ASTBlock.java:147)
at org.apache.velocity.runtime.parser.node.ASTIfStatement.render(ASTIfStatement.java:171)
at org.apache.velocity.runtime.parser.node.SimpleNode.render(SimpleNode.java:439)
at org.apache.velocity.Template.merge(Template.java:358)
at org.apache.velocity.Template.merge(Template.java:262)
at org.xwiki.velocity.internal.DefaultVelocityEngine.evaluate(DefaultVelocityEngine.java:280)
... 185 more
Caused by: org.xwiki.query.QueryException: Exception while executing query. Query statement = [ select doc.fullName from XWikiDocument as doc , BaseObject as topic , com.xpn.xwiki.objects.StringProperty as topic_key1 where ( topic_key1.value = :thisKey ) and doc.fullName=topic.name and topic.className='WaihonaCode.healthTopicsClass' and topic_key1.id.id=topic.id and topic_key1.id.name='key' ]
at com.xpn.xwiki.store.hibernate.query.HqlQueryExecutor.execute(HqlQueryExecutor.java:184)
at org.xwiki.query.internal.DefaultQueryExecutorManager.execute(DefaultQueryExecutorManager.java:72)
at org.xwiki.query.internal.DefaultQuery.execute(DefaultQuery.java:306)
at org.xwiki.query.xwql.internal.XWQLQueryExecutor.execute(XWQLQueryExecutor.java:117)
at org.xwiki.query.internal.DefaultQueryExecutorManager.execute(DefaultQueryExecutorManager.java:72)
at org.xwiki.query.internal.SecureQueryExecutorManager.execute(SecureQueryExecutorManager.java:67)
at org.xwiki.query.internal.DefaultQuery.execute(DefaultQuery.java:306)
at org.xwiki.query.internal.ScriptQuery.execute(ScriptQuery.java:276)
at jdk.internal.reflect.GeneratedMethodAccessor283.invoke(Unknown Source)
at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.base/java.lang.reflect.Method.invoke(Method.java:566)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.doInvoke(UberspectImpl.java:571)
at org.apache.velocity.util.introspection.UberspectImpl$VelMethodImpl.invoke(UberspectImpl.java:554)
at org.apache.velocity.runtime.parser.node.ASTMethod.execute(ASTMethod.java:221)
... 208 more
Caused by: com.xpn.xwiki.XWikiException: Error number 0 in 3: Exception while hibernate execute
at com.xpn.xwiki.store.XWikiHibernateBaseStore.execute(XWikiHibernateBaseStore.java:835)
at com.xpn.xwiki.store.XWikiHibernateBaseStore.executeRead(XWikiHibernateBaseStore.java:902)
at com.xpn.xwiki.store.hibernate.query.HqlQueryExecutor.execute(HqlQueryExecutor.java:169)
... 221 more
Caused by: java.lang.NullPointerException
![Antonie D. Kline, Joanna F. Moss, […]Raoul C. Hennekam](/xwiki/bin/download/cdlsPublications/consensus/WebHome/someAuthors.png?rev=1.1)
Adapted from: Kline, A. D., Moss, J. F., Selicorni, A., Bisgaard, A., Deardorff, M. A., Gillett, P. M., Ishman, S. L., Kerr, L. M., Levin, A. V., Mulder, P. A., Ramos, F. J., Wierzba, J., Ajmone, P.F., Axtell, D., Blagowidow, N., Cereda, A., Costantino, A., Cormier-Daire, V., FitzPatrick, D., Grados, M., Groves, L., Guthrie, W., Huisman, S., Kaiser, F. J., Koekkoek, G., Levis, M., Mariani, M., McCleery, J. P., Menke, L. A., Metrena, A., O’Connor, J., Oliver, C., Pie, J., Piening, S., Potter, C. J., Quaglio, A. L., Redeker, E., Richman, D., Rigamonti, C., Shi, A., Tümer, Z., Van Balkom, I. D. C. and Hennekam, R. C. (2018).
temat trzymający ten temat
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